Friday, November 5, 2021:
| 1230 WBVP-AM, 99.3 FM, and beavercountyradio.com
Western Beaver |
8 42 Final |
| 1460 WMBA and the Trib-Live Network
Ambridge |
6 34 Final |
| WPIAL Class 4A First Round | |
| New Castle Highlands |
31 19 Final |
| Laurel Highlands Beaver |
28 27 Final |
| Montour Armstrong |
16 27 Final |
| WPIAL Class 2A First Round | |
| New Brighton Washington |
21 20 Final |
| Ligonier South Side |
14 34 Final |
| Shady Side Academy Sto-Rox |
8 61 Final |
| WPIAL Class 1A First Round | |
| Mapletown Rochester @ Freedom |
0 35 Final |
| OLSH Greensburg Central |
28 8 Final |